Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303677 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2018 | 14 Pages |
Abstract
In summary, we show functional similarities but also some important differences between GPR84 and FFA2R in human phagocytes, thus providing some mechanistic insights into GPR84 regulation in blood neutrophils and cells recruited to an aseptic inflammatory site in vivo.
Keywords
KRGFFAsIL-8PAFRFPRPBMCsPTXGPCRFCSLatrunculin ARLUC5aRM-CSFPFAAPCSCFAsCTABKrebs-Ringer phosphate bufferMCFAsTNFαFITCHRPBSADMSOG-protein coupled receptorG-protein coupled receptorsMDMsNADPH-oxidaseROSPestbovine serum albuminFree fatty acidsMedium chain fatty acidsShort-chain fatty acidsInterleukin 8tumour necrosis factor αDimethyl sulfoxidefetal calf serumperipheral blood mononuclear cellspertussis toxinconfidence intervalphycoerythrinFluoresceinmacrophage colony-stimulating factormonocyte-derived macrophagesMonocytesNeutrophilsHexadecyltrimethylammonium bromidearbitrary unitsrelative light unitsparaformaldehydeHorseradish peroxidasePenicillin-streptomycinReactive oxygen speciesPlatelet activating factor receptorFormyl peptide receptors
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Authors
Martina Sundqvist, Karin Christenson, André Holdfeldt, Michael Gabl, Jonas MÃ¥rtensson, Lena Björkman, Regis Dieckmann, Claes Dahlgren, Huamei Forsman,