Article ID Journal Published Year Pages File Type
8303859 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2013 11 Pages PDF
Abstract
Our results indicate that N-Ras might contribute to renal fibrosis through the down-regulation of ECM synthesis and up-regulation proliferation and migration modulating Akt activation. N-Ras also regulates TGF-β1-induced collagen I and fibronectin expression through Erk-independent pathways.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts
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