Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303988 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2007 | 8 Pages |
Abstract
⺠The data suggest that DNA ligase III is the replicative DNA ligase in human mitochondria. ⺠RNase H1 is indispensable for Okazaki fragment processing in human mtDNA replication. ⺠On the other hand, knockdown of neither DNA2 nor FEN1 affected mtDNA replication. ⺠Mitochondria utilise distinct proteins for Okazaki fragment maturation from nucleus.
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Authors
Heini Ruhanen, Kathy Ushakov, Takehiro Yasukawa,