Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8303993 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 10 Pages |
Abstract
⺠Cross-talk between SMC-monocytes induces an inflammatory response in both cell types. ⺠Up-regulation of TNFα, CX3CR1 and MMP-9 is dependent on fractalkine/CXRCR1 axis. ⺠IL-1β and IL6 up-regulation is independent of CX3CL1/CX3CR1 pair. ⺠Fractalkine-CX3CR1 binding triggers the activation of AP-1 transcription factor.
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Authors
Elena Dragomir Butoi, Ana Maria Gan, Ileana Manduteanu, Daniela Stan, Manuela Calin, Monica Pirvulescu, Rory Ryan Koenen, Christian Weber, Maya Simionescu,