Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8304002 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 11 Pages |
Abstract
⺠Zac1 enhanced PMA-induced AP-1 activity in HeLa and HeLa/p53 shRNA cells. ⺠Zac1 physically and functionally interacted with AP-1 (c-Jun, c-Fos, or both) proteins. ⺠Zac1 functioned as a selective coactivator for AP-1-dependent transcription. ⺠Zac1 interplayed with PMA on the sub-G1 phase via the phosphorylation of H2A.X.
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Authors
Wei-Ming Wang, Shu-Ting Liu, Shih-Ming Huang, Wei-Shiang Lin, Shyi-Gen Chen, Yung-Lung Chang,