Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8304003 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2011 | 10 Pages |
Abstract
⺠A549 cells stimulate periostin expression in mesenchymal stem cells through lysophosphatidic acid-mediated manner. ⺠Mesenchymal stem cells-derived periostin stimulates in vivo growth of A549 xenograft tumor. ⺠Mesenchymal stem cells-derived periostin stimulates adhesion and proliferation of A549 cells. ⺠Periostin is involved in differentiation of mesenchymal stem cells to carcinoma-associated fibroblasts.
Keywords
α-SMATGF-β1CAFsMSCsLPAshRNAGAPDHDAPI4′,6-diamidino-2-phenylindolehASCsSmall interfering RNAshort hairpin RNAsiRNAlysophosphatidic acidα-smooth muscle actinTransforming growth factor-β1TumorigenesisMesenchymal stem cellsHuman adipose tissue-derived mesenchymal stem cellsCarcinoma-associated fibroblastsPeriostinAdhesionglyceraldehydes-3-phosphate dehydrogenase
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Authors
Soon Chul Heo, Kook One Lee, Sang Hun Shin, Yang Woo Kwon, Young Mi Kim, Chang Hun Lee, Yeong Dae Kim, Min Ki Lee, Man-Soo Yoon, Jae Ho Kim,