| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8304668 | Biochimie | 2015 | 9 Pages |
Abstract
rLj-RGD4 exhibits potent in vivo activity and inhibits the growth of transplanted Hep-2 human laryngeal carcinoma cells in a nude mouse model. Thus, these results indicate that the recombinant RGD toxin protein rLj-RGD4 may serve as a potent clinical therapy for human laryngeal squamous carcinoma.
Keywords
Arg-Gly-AspPI3KMVDECMGAPDHRGDFAKBcl-2qRT-PCRAktBaxTUNELapoptotic indexAnti-tumourVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Phosphatidylinositol 3-kinaseNude miceInhibition rateHEp-2quantitative reverse transcription-polymerase chain reactionBcl-2 Associated X proteinprotein kinase Bfocal adhesion kinaseglyceraldehyde-3-phosphate dehydrogenase
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Authors
Fangyu Shao, Mei Lv, Yuanyuan Zheng, Junshu Jiang, Yue Wang, Li Lv, Jihong Wang,