| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8306001 | Biochimie Open | 2018 | 8 Pages |
Abstract
Because plasma glutathione (GSH) promotes the formation of some F2-IsoPs, we suggest that the surprising decrease in F2-IsoPs levels in older subjects would be caused by decreased GSH under major ROS production in older subjects. We argue that the assessment F2-IsoPs in plasma as biomarkers of the aging process should be challenged by exercise to improve the assessment of the functional response against reactive oxygen species in older subjects.
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Authors
Claire Vinel, Ophélie Pereira, Aude Dupuy, Justine Bertrand-Michel, Dalila Laoudj-Chenivesse, Yves Rolland, Daniel Rivière, Philippe Valet, Cédric Dray, Fabien Pillard,