Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8308959 | Cellular Signalling | 2018 | 30 Pages |
Abstract
These data show dysregulated IL-6 signalling in bronchial fibroblasts derived from severe eosinophilic asthmatic subjects involving the protein tyrosine phosphatase SHP2 and p38MAPK. Collectively, our data provides new insights into the mechanisms by which bronchial fibroblasts regulate airway remodelling in severe asthma.
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Authors
Ikhlass Haj Salem, Sophie Plante, Abdelilah S. Gounni, Mahmoud Rouabhia, Jamila Chakir,