Validation of a simple, fast liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 40 antidepressant drugs or their metabolites in plasma

Article ID	Journal	Published Year	Pages	File Type
8309457	Clinica Chimica Acta	2018	15 Pages	PDF

Keywords

MTBE Liquid chromatography-triple quadrupole mass spectrometry LLOQ ESI EMA m-Chlorophenylpiperazine ACN ULOQ mCPP ISTD LLE cpd European Medicines agency Liquid-liquid extraction Acetonitrile standard deviation collision energy Extraction efficiency upper limit of quantification lower limit of quantification Antipsychotic Retention time Antidepressant coefficient of determination Coefficient of Variation Mass spectrometry Liquid chromatography-tandem mass spectrometry matrix factor Mobile phase confidence interval Selective serotonin reuptake inhibitor SSRI therapeutic drug monitoring Calibration Triple quadrupole cal quality control electrospray ionisation

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Validation of a simple, fast liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 40 antidepressant drugs or their metabolites in plasma

Authors

Maarten Degreef, Alexander L.N. van Nuijs, Kristof E. Maudens,