| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8309481 | Clinica Chimica Acta | 2018 | 7 Pages |
Abstract
A bioanalytical assay for IMPDH quantification was optimized and evaluated. The differences in the pharmacodynamics of MPA between Asians and Caucasians may provide some evidence for dosing differences among ethnicities.
Keywords
GMPIMPDHQCsPBMCsMMFIMPMPATDMInosine 5′-monophosphate dehydrogenaseTBAsAMPRSDPharmacodynamic biomarkerXMPAECAUCBSAadenosine monophosphatebovine serum albuminrelative standard deviationrelative errorperipheral blood mononuclear cellsPharmacodynamicsPharmacokineticsmycophenolate mofetilmycophenolic acidArea under the concentration-time curveInosine monophosphateNADtherapeutic drug monitoringquality control samplesnicotinamide adenine dinucleotidehigh performance liquid chromatographyhigh-performance liquid chromatographyHPLCGuanosine monophosphate
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Authors
Feiyan Liu, Luyang Xu, Changcheng Sheng, Xiaoyan Qiu, Ming Zhang, Zheng Jiao,