Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8309561 | Clinica Chimica Acta | 2018 | 6 Pages |
Abstract
EOC patients showed significantly higher levels for IL-6 (median-5636â¯pg/ml) and VEGF-A (median-4556â¯pg/ml) in ascitic fluid compared to controls. Levels of IL-6 and VEGF-A significantly correlated with clinico-pathological parameters. ROC curves of IL-6 and VEGF-A showed absolute combination of sensitivity and specificity. Kaplan Meier analysis demonstrated that higher levels of IL-6 and VEGF-A were significantly associated with shorter progression free survival. Thus, this study revealed that IL-6 and VEGF-A have great potential to be used as superior bio-markers for progression free survival in future after validation in larger patients' cohort.
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Authors
Venus Dalal, Raman Kumar, Sunesh Kumar, Alpana Sharma, Lalit Kumar, Jai Bhagwan Sharma, Kallol Kumar Roy, Neeta Singh, Perumal Vanamail,