Article ID Journal Published Year Pages File Type
8312842 Clinica Chimica Acta 2013 7 Pages PDF
Abstract
Plasma lysoGb3 is a more sensitive and reliable biomarker than plasma Gb3. LysoGb3 also correlated with age and left ventricular mass index in Fabry patients with IVS4 + 919G>A mutation. Because lots of infants with the IVS4 + 919G>A mutation already had elevated lysoGb3 levels at birth, that indicates that the development of hypertrophic cardiomyopathy may require a long and insidious course after lysoGb3 accumulation.
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