| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8313121 | Clinica Chimica Acta | 2013 | 7 Pages |
Abstract
Digital microfluidic technology shows potential for rapid, high-throughput screening for 5 LSDs in a newborn screening laboratory environment. Sample preparation to enzymatic activity on each cartridge is less than 3Â h.
Keywords
IDSQCH4-Methyl umbelliferoneQCLLSDsRFU4-MUGalNAcCLSIGAANBSIdUDBSCDCGLAGBADMSOdigital microfluidicsN-Acetyl-D-GalactosamineAcid α-glucosidaseLysosomal storage diseaseLysosomal storage diseasesHigh throughputDimethyl sulfoxideNewborn screeningmethyl-β-cyclodextrinCenters for Disease Control and PreventionClinical and Laboratory Standards InstituteQCMDried blood spotALLRelative Fluorescence Units
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Authors
Ramakrishna S. Sista, Tong Wang, Ning Wu, Carrie Graham, Allen Eckhardt, Theodore Winger, Vijay Srinivasan, Deeksha Bali, David S. Millington, Vamsee K. Pamula,