| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8313454 | Clinica Chimica Acta | 2013 | 8 Pages |
Abstract
⺠There is a lack of methodologies to get a full profile of lipid classes in blood. ⺠We optimized an HPLC-ELSD to quantify lipid classes in human blood. ⺠We compare the lipid class profile in blood of cirrhotics and healthy controls. ⺠We found alterations in the PC/PE ratio measured in plasma of cirrhotics. ⺠We described alterations in erythrocyte acidic phospholipids of cirrhotics.
Keywords
sphyngomyelinELSDISTDNPLCSPMLC-MSLOQFFAESI-MSTHFEvaporative Light Scattering DetectorElectrospray Ionization Mass SpectrometryFree fatty acidsTetrahydrofurantriglycerideLOD یا Limit of detectionRetention timeliver cirrhosisCoefficient of VariationMass spectrometryLiquid chromatography mass spectrometryphosphatidylinositolphosphatidylcholinePhosphatidylserineLipidomicsLipid metabolismlimit of quantificationlimit of detectionModel of End Stage Liver DiseasemonoglyceridesHILICCardiolipinChromatographyNormal phase chromatographyhigh performance liquid chromatographyHPLCTotal phospholipidsLipid classescholesteryl estertotal cholesterolfree cholesterolMELD
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Authors
Laura Chamorro, Ana GarcÃa-Cano, Rebeca Busto, Javier MartÃnez-González, AgustÃn Albillos, Miguel Ángel Lasunción, Ãscar Pastor,