| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8313478 | Clinica Chimica Acta | 2013 | 7 Pages |
Abstract
It is likely that cholesterolemia status changes promoted by atorvastatin play a role in regulating CYP3A4 and CYP3A5 mRNA expression in PBMCs, as well as CYP3A activity. CYP3A5*3C (AGT haplotype) also contributes for the variability of CYP3A5 mRNA levels in PBMCs.
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Authors
Maria Alice V. Willrich, Alice C. Rodrigues, Alvaro Cerda, Fabiana D.V. Genvigir, Simone S. Arazi, Egidio L. Dorea, Marcia M.S. Bernik, Marcelo C. Bertolami, Andre Faludi, Alvaro Largura, Linnea M. Baudhuin, Sandra C. Bryant, Mario Hiroyuki Hirata,