High expression of interleukin 10 might predict poor prognosis in early stage oral squamous cell carcinoma patients

► Interleukin 10 (IL10) influences tumorigenesis in oral squamous cell carcinoma. ► IL10 is important in immunosuppression and suppression of antitumor immunity. ► IL10 expression is significantly associated with aggressive clinical manifestations. ► IL10 expression might independently predict survival, especially in early stage OSCC.