Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy

Article ID	Journal	Published Year	Pages	File Type
8313700	Clinica Chimica Acta	2013	6 Pages	PDF

Abstract

âº Construction of a new blood score for fibrosis staging in chronic hepatitis C. âº Two unusual markers were included: osteoprotegerin and collagen IV. âº This score shows better diagnostic performance than other non-invasive methods.

Keywords

OPG CHC AUROC PPV RANKL apoA1 GST A2M ROC TIMP1 MMP1 GGT PIIIP procollagen III peptide natural killer AST Aspartate aminotransferase alpha-2-macroglobulin Apolipoprotein A1 positive predictive value negative predictive value Osteoprotegerin Hyaluronic acid standard deviation liver stiffness measurement optic density LSM body mass index BMI Platelet count confidence interval Liver fibrosis Matrix metalloproteinase 1 Area under receiver operating characteristic curve NPV یا negative predictive value Receiver operating characteristic curve Tissue inhibitor of metalloproteinase 1 chronic hepatitis C HCV Hepatitis C virus plat total bilirubin Collagen IV Gamma glutamyl transpeptidase receptor activator of nuclear factor kappa B ligand

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy

Authors

Nelly Bosselut, Ludmia Taibi, JérÃ´me Guéchot, Jean-Pierre Zarski, Nathalie Sturm, Marie-Christine Gelineau, Bernard Poggi, Sophie Thoret, Elisabeth Lasnier, Bruno Baudin, Chantal Housset, Michel Vaubourdolle,