Article ID Journal Published Year Pages File Type
8313812 Clinica Chimica Acta 2013 7 Pages PDF
Abstract
► We developed a method that allows for analysis of PON-1 enzymatic activity in HDL subclasses. ► It employs polyacrylamide gradient gels and phenylacetate as substrate with detection of product of coupled reaction. ► At the same HDL-C level, healthy subjects display a large difference in the ratio of PON-1 activity in small vs. large HDL. ► We propose that this difference has a potent predictive value for clinical risk assessment and therapeutic choice.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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