| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8314119 | Clinica Chimica Acta | 2012 | 5 Pages |
Abstract
⺠We evaluated the cross-reactivity in tacrolimus CLIA in kidney transplantation. ⺠CYP3A5*3 affected the metabolic pathway of tacrolimus and its blood level. ⺠Blood tacrolimus level measured by CLIA was 35% higher than that by LC-MS/MS. ⺠A higher cross-reactivity was found in patients with a tacrolimus level of < 3 μg/l. ⺠A higher cross-reactivity was found in patients with the CYP3A5*1 allele.
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Authors
Kumi Hirano, Takafumi Naito, Yasuaki Mino, Tatsuya Takayama, Seiichiro Ozono, Junichi Kawakami,