Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8314262 | Clinica Chimica Acta | 2012 | 8 Pages |
Abstract
⺠This LC-MS/MS technique allows quantification of lyso-Gb3 in plasma. ⺠The chemical structure of lyso-Gb3 was confirmed by tandem mass spectrometry fragmentation. ⺠The validation of the plasma lyso-Gb3 method provided good accuracy and precision. ⺠Plasma lyso-Gb3 levels were markedly decreased following the beginning of ERT. ⺠The plasma lyso-Gb3 methodology developed is robust and user-friendly.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Michel Boutin, René Gagnon, Pamela Lavoie, Christiane Auray-Blais,