| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8314433 | Clinica Chimica Acta | 2012 | 6 Pages |
Abstract
⺠Altered PSA glycosylation occurs during malignant transformation of the prostate. ⺠Altered glycosylation of tissue, semen, serum and urine PSA has been described. ⺠Pre-analytical issues are of utmost importance. ⺠Sensitivity of conventional glycosylation analysis is insufficient for discovery. ⺠High-throughput lectin based platforms can be used to monitor disease progress.
Keywords
SPEGPHA-LSNAPCIAMACRuPARPCA3proPSAtPSAGSTP1PHA-EPSMAsEMGHK2SLexα-methylacyl-CoA racemaseSemenogelinUEASambucus nigra agglutininBPSAPhaseolus vulgaris erythroagglutininLIFMaackia amurensis lectinPhaseolus vulgaris leukoagglutininqRT-PCRConcanavalin APSAROCSRMMAL2-DEfPSALC-MS/MSMS/MSsialyl Lewis XAleuria aurantia agglutininProstate specific antigenProstate Cancer Antigen 3Prostate-specific membrane antigenTwo-dimensional electrophoresisCapillary electrophoresisELLACon Afree PSAProstate cancerMass spectrometryTandem mass spectrometryLiquid chromatography-tandem mass spectrometryLaser induced fluorescenceLectinselected reaction monitoringIsoelectric pointBenign prostatic hyperplasiaBPHProtein C inhibitorHPLChigh-performance liquid chromatographytotal PSAGlycosylationreceiver operating characteristicUrokinase-type plasminogen activator receptorUlex europaeus
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Authors
Tijl Vermassen, Marijn M. Speeckaert, Nicolaas Lumen, Sylvie Rottey, Joris R. Delanghe,