Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8314783 | Clinica Chimica Acta | 2012 | 8 Pages |
Abstract
⺠IL-1 family has a central role in regulation of immune and inflammatory responses. ⺠IL-1 regulates basic metabolic rate, blood glucose levels, blood pressure etc. ⺠IL-1 family consists of both pro- and anti-inflammatory cytokines. ⺠IL-1 impairs insulin secretion and induces β-cell apoptosis leading to T2D. ⺠IL-1 gene polymorphisms are T2D susceptibility indicators in different populations.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Monisha Banerjee, Madhukar Saxena,