Article ID Journal Published Year Pages File Type
8314783 Clinica Chimica Acta 2012 8 Pages PDF
Abstract
► IL-1 family has a central role in regulation of immune and inflammatory responses. ► IL-1 regulates basic metabolic rate, blood glucose levels, blood pressure etc. ► IL-1 family consists of both pro- and anti-inflammatory cytokines. ► IL-1 impairs insulin secretion and induces β-cell apoptosis leading to T2D. ► IL-1 gene polymorphisms are T2D susceptibility indicators in different populations.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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