Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8315252 | Clinica Chimica Acta | 2012 | 7 Pages |
Abstract
⺠The influence of genetic variants on atorvastatin response was evaluated. ⺠Atorvastatin treatment is influenced by G allele for â 290A>G variant of CYP3A4. ⺠The carriers of the G allele for the â 290A>G variant have lower CYP3A4 activity. ⺠The variant â 290A>G of CYP3A4 could be used as a pharmacogenetic predictor.
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Authors
Alexy Rosales, Marysol Alvear, Alejandro Cuevas, Nicolás Saavedra, Tomás Zambrano, Luis A. Salazar,