Article ID Journal Published Year Pages File Type
8315252 Clinica Chimica Acta 2012 7 Pages PDF
Abstract
► The influence of genetic variants on atorvastatin response was evaluated. ► Atorvastatin treatment is influenced by G allele for − 290A>G variant of CYP3A4. ► The carriers of the G allele for the − 290A>G variant have lower CYP3A4 activity. ► The variant − 290A>G of CYP3A4 could be used as a pharmacogenetic predictor.
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