| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8315274 | Clinica Chimica Acta | 2012 | 4 Pages |
Abstract
⺠We compared mutant levels by AS-qPCR with autologous DNA percentage by STR-PCR. ⺠Single nucleotide mutations are considered one of the MRD markers in leukemia. ⺠AS-qPCR detected mutant DNAs at a quantifiable level before relapse in complete chimerism. ⺠AS-qPCR for single nucleotide mutations was accurate and highly sensitive for monitoring MRD.
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Authors
Chiaki Taira, Kazuyuki Matsuda, Shoji Saito, Kazuo Sakashita, Mitsutoshi Sugano, Nobuo Okumura, Takayuki Honda,