Article ID Journal Published Year Pages File Type
8315274 Clinica Chimica Acta 2012 4 Pages PDF
Abstract
► We compared mutant levels by AS-qPCR with autologous DNA percentage by STR-PCR. ► Single nucleotide mutations are considered one of the MRD markers in leukemia. ► AS-qPCR detected mutant DNAs at a quantifiable level before relapse in complete chimerism. ► AS-qPCR for single nucleotide mutations was accurate and highly sensitive for monitoring MRD.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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