Article ID Journal Published Year Pages File Type
8315367 Clinica Chimica Acta 2012 7 Pages PDF
Abstract
► The effect of estrogens and of ERα on the cardiovascular system is described. ► E2 and ERα exert their function acting via genomic and non-genomic mechanisms. ► In animals, ERα activation reduces infarct size, inflammation, and oxidative stress. ► It also induces vasodilatation and increases neovascularization. ► The cardioprotective role of ERα in humans is not fully elucidated.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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