| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8315419 | Clinica Chimica Acta | 2012 | 8 Pages |
Abstract
⺠The MMP-9 -1562 T-allele associated significantly with elevated serum MMP-9 levels. ⺠The MMP-9 R279Q G-allele was related to lower MMP-9 activity and hypertension. ⺠The T- and G-alleles induced lower and higher MMP-9 mRNA levels, respectively. ⺠Elevated TIMP-1 levels were related to myocardial infarction and type 2 diabetes.
Keywords
APMAT2DMTIMP-1MMP-9HDLDBPSBPmRNALPSp-aminophenylmercuric acetateenzyme linked immuno sorbent assayMyocardial infarctioncoronary artery diseasecardiovascular diseaseELISAtype-2 diabetes mellitusCVDZymographybody mass indexBMICADLinkage disequilibriumHypertensiondiastolic blood pressuresystolic blood pressurehigh density lipoproteinlow density lipoproteinLDLlipopolysaccharideMatrix metalloproteinase-9polymerase chain reactionPCRSingle nucleotide polymorphismSNP
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Authors
Trine B. Opstad, Alf-Aage R. Pettersen, Thomas W. Weiss, Sissel Ã
kra, Reidun Ãvstebø, Harald Arnesen, Ingebjørg Seljeflot,