Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8315768 | Clinica Chimica Acta | 2011 | 7 Pages |
Abstract
⺠Knowledge of VKORC1 and CYP2C9 genotype is of value in setting initial coumarin anticoagulant dose. ⺠A rapid real-time PCR genotyping assay for VKORC1 and CYP2C9 is described. ⺠The assay uses whole blood and can be done at point of care by clinical staff. ⺠The assay was validated successfully in 156 individuals.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Rebecca Howard, Julian B.S. Leathart, David J. French, Elaina Krishan, Hugo Kohnke, Mia Wadelius, Rianne van Schie, Talitha Verhoef, Anke-Hilse Maitland-van der Zee, Ann K. Daly, Rita Barallon,