Article ID Journal Published Year Pages File Type
8315787 Clinica Chimica Acta 2011 9 Pages PDF
Abstract
► We used the second tier steroid profile by LC-MS/MS in conjunction with EIA. ► The three steroid profile provided better screening outcomes of CAH than 17-OHP concentration alone. ► Our sample preparation allowed high throughput using common laboratory chemicals. ► Using three internal standards significantly improved method precision and accuracy. ► The reduction in false positives significantly reduces anxiety for newborns and their families.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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