Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8315947 | Clinica Chimica Acta | 2011 | 6 Pages |
Abstract
⺠Cytokeratin-1 was identified at 67 kDa and quantified in sera of HCC patients using western blot and ELISA. ⺠MD analysis selected a score for the prediction of HCC vs liver cirrhosis patients based on levels of CK1, albumin and AFP. ⺠An area under ROC curves (AUC) of the score was 0.87. ⺠The score showed 87% sensitivity vs 39% sensitivity of AFP at cutoff value of 200 IU/ml for prediction of HCC from LC. ⺠Absolute specificity (100%) was obtained to discriminate HCC from healthy individual
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Authors
Abdelfattah M. Attallah, Mohamed El-Far, Camelia A. Abdel Malak, Faten Zahran, Khaled Farid, Mohamed M. Omran, Hayat Zagloul, Mohamed S. El-Deen,