| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8316122 | Clinica Chimica Acta | 2011 | 5 Pages |
Abstract
⺠LH-MSA is a simple method for detection of point-mutations. ⺠LH-MSA detected 12 mutations of KRAS in codons 12 and 13. ⺠The insert type LH-probe provided a way to detect these 12 mutations. ⺠Our method differentiated all KRAS mutations detected in colorectal tumor DNA. ⺠LH-MSA detected KRAS mutations in colorectal tumor DNA with 5% mutant sensitivity.
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Authors
Shoichi Matsukuma, Mitsuyo Yoshihara, Tetsuji Suda, Manabu Shiozawa, Makoto Akaike, Tomokazu Ishikawa, Shiro Koizume, Yuji Sakuma, Yohei Miyagi,