Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8316554 | Clinica Chimica Acta | 2011 | 4 Pages |
Abstract
Although the most common diagnostic method for screening CSF leakage is glucose oxidase, its diagnostic sensitivity and specificity is generally unsatisfactory. False negative results may occur with bacterial contamination and false positive results are common in diabetic patients. Glucose detection is not recommended as a confirmatory test. As such, other biomarkers of the CSF leakage, such as beta-2-transferrin (beta-2 trf) and beta-trace protein (betaTP) are necessary to identify and confirm of this condition.
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Authors
Maria Mantur, Marta Åukaszewicz-ZajÄ
c, Barbara Mroczko, Alina KuÅakowska, Oliver Ganslandt, Halina Kemona, Maciej Szmitkowski, WiesÅaw Drozdowski, Rüdiger Zimmermann, Johannes Kornhuber, Piotr Lewczuk,