Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8316847 | Clinical Biochemistry | 2018 | 9 Pages |
Abstract
Evaluation of NIPT assay performances therefore requires knowledge of the FF distribution in the population in which the test is intended to be used and, in particular, of the precise value of the assay chrratio CV for each chromosome or genomic region of interest. Laboratories offering NIPT testing should carefully measure these parameters to ensure test reliability and clinical usefulness in interpreting individual patients' results.
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Authors
Jonatan Blais, Sylvie Giroux, André Caron, Valérie Clément, Alexandre Dionne-Laporte, Loubna Jouan, Julie Gauthier, Tina MacLeod, Richard Moore, Jeremy Parker, Lucas Swanson, Yongjun Zhao, Guy Rouleau, Aly Karsan, Sylvie Langlois, François Rousseau,