| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8316878 | Clinical Biochemistry | 2018 | 8 Pages |
Abstract
To our knowledge, this is the first study that experimentally verifies the trypsin-like activity of KLK15. We show here for the first time that KLK15 may be able to cleave many ECM components, similar to several members of the KLK family. Thus the protease could potentially be linked to tumorigenesis by promoting metastasis via this mechanism.
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Authors
Panagiota S. Filippou, Annie H. Ren, Sudarshan Bala, Michail-Dimitrios Papaioannou, Davor Brinc, Ioannis Prassas, Theano Karakosta, Eleftherios P. Diamandis,