| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8317041 | Clinical Biochemistry | 2018 | 6 Pages |
Abstract
Our results demonstrate that for 27-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 7α-hydroxycholesterol and lanosterol, a single serum measurement can reliably estimate average levels over a one-year period. Circulating oxysterols are of increasing interest in epidemiologic studies of chronic disease risk including cancer and cardiovascular disease. Our data suggest that within-person stability of oxysterols differs depending on the individual oxysterol evaluated. We identified four oxysterols and lanosterol as stable over time to inform the use of circulating oxysterols in epidemiologic studies.
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Authors
Da-Lin Lu, Disorn Sookthai, Charlotte Le Cornet, Verena A. Katzke, Theron S. Johnson, Rudolf Kaaks, Renée T. Fortner,