| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8317121 | Clinical Biochemistry | 2017 | 12 Pages |
Abstract
- Malnutrition is a risk factor of hyperammonemia and 5-oxoprolinuria.
- Hyperammonemia may be responsible for encephalopathy, even if it is marginally increased.
- 5-oxoproline may be a source of glutamate in astrocytes, accelerating glutamine synthesis in the brain.
- Consider asking patients suffering from malnutrition for these parameters.
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Authors
Guillaume Rousseau, Isabelle Signolet, Marie-Christine Denis, Juan Manuel Chao de la Barca, Rafaël Mahieu, Franck Letournel, Pascal Reynier, Gilles Simard,