Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8317138 | Clinical Biochemistry | 2017 | 37 Pages |
Abstract
A method for sensitive and selective quantification of plasma total and free itraconazole and hydroxyitraconazole concentrations was developed using UPLC-MS/MS. Free hydroxyitraconazole concentration may be most important in therapeutic drug monitoring of itraconazole.
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Authors
Yosuke Suzuki, Ryota Tanaka, Nobuhiro Oyama, Ko Nonoshita, Kazuhiko Hashinaga, Kenji Umeki, Yuhki Sato, Kazufumi Hiramatsu, Jun-ichi Kadota, Hiroki Itoh,