A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development

Article ID	Journal	Published Year	Pages	File Type
8317192	Clinical Biochemistry	2015	9 Pages	PDF

Keywords

Jnk eNOS HOMA-IR AP-1 ERK IRS-1 FFA NAC GSH GLUT PDX-1 Jun N-terminal kinase IKKβ CCL2 LPS TNFα I-κB PTP1B NF-κB PI3-kinase STAT3 N-acetylcysteine ROS Antioxidant Akt homeostasis model assessment of insulin resistance Free fatty acid insulin receptor substrate-1 interleukin Inhibitor of κB kinase tumor necrosis factor α Glucose transporter endothelial nitric oxide synthase Anti-apoptotic Anti-inflammatory nuclear factor κB Phosphatidylinositol 3-kinase lipopolysaccharide signal transducer and activator of transcription 3 Insulin resistance inhibitor of NF-κB Nitric oxide activator protein 1 protein kinase B reduced glutathione chemokine (C–C motif) ligand 2 extracellular signal-regulated kinase Sulfhydryl group Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development

Authors

Mohamed Montassar Lasram, Ines Bini Dhouib, Alya Annabi, Saloua El Fazaa, Najoua Gharbi,