| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8317562 | Clinical Biochemistry | 2014 | 6 Pages |
Abstract
We found frequent PIK3CA amplification and promoter methylation of RASSF1A and PAX6 genes in gastric cancers, and demonstrated that concomitant PIK3CA amplification and promoter methylation in any one of these two genes were significantly associated with worse survival in gastric cancer. Collectively, such (epi)genotypes may be strong and independent poor prognostic factors for gastric cancer patients.
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Authors
Qi Yang, Yuan Shao, Jing Shi, Yiping Qu, Kexia Wu, Siwen Dang, Bingyin Shi, Peng Hou,