Soluble TNFÎ± receptor type I and hepcidin as determinants of development of anemia in the long-term follow-up of heart failure patients

Article ID	Journal	Published Year	Pages	File Type
8317817	Clinical Biochemistry	2012	4 Pages	PDF

Abstract

âº Patients with heart failure who are still non-anemic were studied. âº Parameters of iron metabolism, inflammation and myocardial stress were measured. âº A higher sTNFRI at baseline predicted a significant decrease in hemoglobin at 1-year. âº The increase in hepcidin over time was also associated with a decrease in hemoglobin. âº Inflammation and iron metabolism were the main determinants of anemia development.

Keywords

sTNFRI NT proBNP GDF15 sTfR ChF IL6 inflammation interleukin-6 High sensitivity troponin T Growth differentiation factor 15 Iron metabolism heart failure Chronic heart failure C-reactive protein CRP Anemia Soluble transferrin receptor

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Soluble TNFÎ± receptor type I and hepcidin as determinants of development of anemia in the long-term follow-up of heart failure patients

Authors

A. MartÃnez-Ruiz, P.L. Tornel-Osorio, J. Sánchez-Más, J. Pérez-Fornieles, J.A. VÃlchez, P. MartÃnez-Hernández, D.A. Pascual-Figal,