| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8317922 | Clinical Biochemistry | 2012 | 8 Pages |
Abstract
⺠We analyzed the tear proteome of diabetic retinopathy (DR) patients. ⺠We have identified different 2-DE maps of tear from DR patients and healthy subjects. ⺠Several down- and up-regulated proteins were identified by ESI-Q-TOF MS/MS. ⺠Three proteins may constitute potential biomarkers for the diagnosis of early DR.
Keywords
PAGEHbA1cNPDRb2mDTTHsp 27BPbtear proteinIEF2-DEDMRESI-Q-TOFElectrospray ionization quadrupole time-of-flight3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonateIPGimmobilized pH gradientTwo-dimensional electrophoresistwo-dimensional gel electrophoresispolyacrylamide gel electrophoresisBromophenol Blueisoelectric focusingdithiothreitoldiabetic retinopathynonproliferative diabetic retinopathyProliferative diabetic retinopathyLipocalin-1Beta-2 microglobulinIsoelectric pointGlycated hemoglobinHeat shock protein 27CHAPS
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Authors
Hyun-Jung Kim, Pan-Kyeom Kim, Hyun-Syuk Yoo, Chan-Wha Kim,