Exposure to 4100Â K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin

Here, we compare RNA-Seq results analyzed to assess changes in the global transcription profiles of female and male X. maculatus skin in response to 4100 K FL exposure. Our results suggest 4100 K FL exposure incites a sex-biased genetic response including up-modulation of inflammation in females and down modulation of DNA repair/replication in males. In addition, we identify clusters of genes that become oppositely modulated in males and females after FL exposure that are principally involved in cell death and cell proliferation.