Article ID Journal Published Year Pages File Type
8319716 Current Opinion in Structural Biology 2016 7 Pages PDF
Abstract
RNA molecules have key functions in cellular processes beyond being carriers of protein-coding information. These functions are often dependent on the ability to form complex three-dimensional (3D) structures. However, experimental determination of RNA 3D structures is difficult, which has prompted the development of computational methods for structure prediction from sequence. Recent progress in 3D structure modeling of RNA and emerging approaches for predicting RNA interactions with ions, ligands and proteins have been stimulated by successes in protein 3D structure modeling.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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