Article ID Journal Published Year Pages File Type
8319786 Current Opinion in Structural Biology 2016 12 Pages PDF
Abstract

- Unwinding a DNA duplex poses topological challenges to replication and transcription.
- Cells have many energy-dependent strategies for maintaining topological homeostasis.
- NTP-fueled molecular machines shape the topological landscape of the genome.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The role of ATP-dependent machines in regulating genome topology
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