Article ID Journal Published Year Pages File Type
8319952 Current Opinion in Structural Biology 2015 10 Pages PDF
Abstract

- Substitution of canonical histones with variants is crucial for nucleosome function.
- Variant H2A-H2B dimers are recognized and substituted as a distinct unit.
- H2A/H2B variants may preferentially associate with each other.
- L1/L2 loops within H2A histone fold have increased sequence and structural variability.
- Variant nucleosomes have altered structural and interaction properties.
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