Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8319952 | Current Opinion in Structural Biology | 2015 | 10 Pages |
Abstract
- Substitution of canonical histones with variants is crucial for nucleosome function.
- Variant H2A-H2B dimers are recognized and substituted as a distinct unit.
- H2A/H2B variants may preferentially associate with each other.
- L1/L2 loops within H2A histone fold have increased sequence and structural variability.
- Variant nucleosomes have altered structural and interaction properties.
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Authors
Alexey K Shaytan, David Landsman, Anna R Panchenko,