| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8320151 | Current Opinion in Structural Biology | 2014 | 8 Pages |
Abstract
- PfMATE-binding macrocyclic peptides were selected.
- No proteinaceous scaffolds were designed into the naïve macrocyclic peptide library.
- Four of the selected macrocyclic peptides were cocrystallized with PfMATE.
- Macrocyclic peptides bound in PfMATE's cleft or substrate-binding pocket.
- The potential of macrocyclic peptides for cocrystallization is discussed.
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Authors
Christopher J Hipolito, Nasir K Bashiruddin, Hiroaki Suga,