Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8320491 | DNA Repair | 2016 | 13 Pages |
Abstract
Nucleotide excision repair (NER) is essential for removing many types of DNA lesions from the genome, yet the mechanisms of NER in humans remain poorly understood. This review summarizes our current understanding of the structure, biochemistry, interaction partners, mechanisms, and disease-associated mutations of one of the critical NER proteins, XPA.
Keywords
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Biochemistry
Authors
Norie Sugitani, Robert M. Sivley, Kelly E. Perry, John A. Capra, Walter J. Chazin,