Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8320534 | DNA Repair | 2016 | 9 Pages |
Abstract
DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences.
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Biochemistry
Authors
Khek-Chian Tham, Roland Kanaar, Joyce H.G. Lebbink,