Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1

Article ID	Journal	Published Year	Pages	File Type
8320603	DNA Repair	2015	13 Pages	PDF

Keywords

TBE PCNA STO FCL Hus1 TBST BER GFP MBP SIFT THF IDC 8-oxoguanine DNA glycosylase MOI Electrophoretic mobility shift assay AST proliferation cell nuclear antigen Escherichia coli Tev Tris-Borate-EDTA Base excision repair (BER)base excision repair Active site titration double-stranded Colorectal cancer EMSA یا electrophoretic mobility shift assay Enzyme kinetics Sorting Intolerant From Tolerant map Tobacco etch virus base-pair green fluorescent protein maltose-binding protein Single nucleotide polymorphisms MUTYH-associated polyposis multiplicity of infection CRC single turnover

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1

Authors

Megan K. Brinkmeyer, Sheila S. David,