Article ID Journal Published Year Pages File Type
8320606 DNA Repair 2015 10 Pages PDF
Abstract

- BER enzymes based assay was developed to measure ɛ-adducts repair by AlkBs.
- Many bacterial AlkBs can repair ɛ-adducts.
- Xanthomonas campestris and Rhizobium etli encode AlkB proteins specialized for ɛ-adducts repair.
- Human AlkBH2 and three of nine bacterial AlkBs repair 1,N2-ɛG.
- Nucleotide recognition lid is not the sole determinant of AlkBs substrate specificity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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